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Rat Rpl7 cDNA Clone(NM_001100534.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005090

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Gene Information

Cat. No. CDFR005090
Description NativeORF clone of Rattus norvegicus ribosomal protein L7 (Rpl7) as transfection-ready DNA NM_001100534.1
Product Type cDAN Clone
Gene Abbr Rpl7
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RPL7
Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
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