Rat Rpl5 cDNA Clone(NM_031099.1)

Name: Rat Rpl5 cDNA Clone(NM_031099.1)
SKU: CDFR012570
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012570

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Product Information

Gene Information

Cat. No.	CDFR012570
Description	NativeORF clone of Rattus norvegicus ribosomal protein L5 (Rpl5) as transfection-ready DNA NM_031099.1
Product Type	cDAN Clone
Gene Abbr	Rpl5
Species	Rat
Vector	pCMV6Entry

Target Gene

RPL5

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Mar 2017]

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