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Rat Rnf19a ORF Clone(NM_001130560.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR376750

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Gene Information

Cat. No. CDCR376750
Product Type ORF Clone
Gene Abbr Rnf19a
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2523 bp
Vector pCMV6-Entry
Target Gene RNF19A
Background This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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