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Rat Rnf14 cDNA Clone(NM_001034995.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004445

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Gene Information

Cat. No. CDFR004445
Description NativeORF clone of Rattus norvegicus ring finger protein 14 (Rnf14) as transfection-ready DNA NM_001034995.1
Product Type cDAN Clone
Gene Abbr Rnf14
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RNF14
Background The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
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