Rat Rnf103 cDNA Clone(NM_053438.2)

Name: Rat Rnf103 cDNA Clone(NM_053438.2)
SKU: CDFR013180
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013180

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Product Information

Gene Information

Cat. No.	CDFR013180
Description	NativeORF clone of Rattus norvegicus ring finger protein 103 (Rnf103) as transfection-ready DNA NM_053438.2
Product Type	cDAN Clone
Gene Abbr	Rnf103
Species	Rat
Vector	pCMV6Entry

Target Gene

RNF103

Background

The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]

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