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Rat Rin2 cDNA Clone(NM_001107786.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007413

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Gene Information

Cat. No. CDFR007413
Description NativeORF clone of Rattus norvegicus Ras and Rab interactor 2 (Rin2) as transfection-ready DNA NM_001107786.1
Product Type cDAN Clone
Gene Abbr Rin2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RIN2
Background The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
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