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Rat Rgc32 cDNA Clone(NM_054008.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013710

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Gene Information

Cat. No. CDFR013710
Description NativeORF clone of Rattus norvegicus response gene to complement 32 (Rgc32) as transfection-ready DNA NM_054008.1
Product Type cDAN Clone
Gene Abbr Rgc32
Species Rat
Vector pCMV6Entry
Target Gene RGCC
Background This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]
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