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Rat Rfx1 cDNA Clone(NM_001105944.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005718

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Gene Information

Cat. No. CDFR005718
Description NativeORF clone of Rattus norvegicus regulatory factor X, 1 (influences HLA class II expression) (Rfx1) as transfection-ready DNA NM_001105944.1
Product Type cDAN Clone
Gene Abbr Rfx1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RFX1
Background This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016]
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