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Rat Rcan1 cDNA Clone(NM_153724.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014668

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Gene Information

Cat. No. CDFR014668
Description NativeORF clone of Rattus norvegicus regulator of calcineurin 1 (Rcan1) as transfection-ready DNA NM_153724.2
Product Type cDAN Clone
Gene Abbr Rcan1
Species Rat
Vector pCMV6Entry
Target Gene RCAN1
Background The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
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