Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR009406
| Cat. No. | CDFR009406 |
| Description | NativeORF clone of Rattus norvegicus retinoblastoma binding protein 8 (Rbbp8) as transfection-ready DNA NM_001134417.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Rbbp8 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | RBBP8 |
| Background | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008] |
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