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Rat Rbbp8 cDNA Clone(NM_001134417.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009406

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Gene Information

Cat. No. CDFR009406
Description NativeORF clone of Rattus norvegicus retinoblastoma binding protein 8 (Rbbp8) as transfection-ready DNA NM_001134417.1
Product Type cDAN Clone
Gene Abbr Rbbp8
Species Rat
Vector pCMV6Entry
Target Gene RBBP8
Background The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
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