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Rat Rbbp4 cDNA Clone(NM_001107912.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007557

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Gene Information

Cat. No. CDFR007557
Description NativeORF clone of Rattus norvegicus retinoblastoma binding protein 4 (Rbbp4) as transfection-ready DNA NM_001107912.2
Product Type cDAN Clone
Gene Abbr Rbbp4
Species Rat
Vector pCMV6Entry
Target Gene RBBP4
Background This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
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