Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR004903
| Cat. No. | CDFR004903 |
| Description | NativeORF clone of Rattus norvegicus Rap guanine nucleotide exchange factor (GEF) 5 (Rapgef5) as transfection-ready DNA NM_001047915.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Rapgef5 |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | RAPGEF5 |
| Background | Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008] |
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