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Rat Rapgef5 cDNA Clone(NM_001047915.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004903

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Gene Information

Cat. No. CDFR004903
Description NativeORF clone of Rattus norvegicus Rap guanine nucleotide exchange factor (GEF) 5 (Rapgef5) as transfection-ready DNA NM_001047915.1
Product Type cDAN Clone
Gene Abbr Rapgef5
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene RAPGEF5
Background Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
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