Rat Rae1 cDNA Clone(NM_001033708.1)

Name: Rat Rae1 cDNA Clone(NM_001033708.1)
SKU: CDFR004269
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004269

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Product Information

Gene Information

Cat. No.	CDFR004269
Description	NativeORF clone of Rattus norvegicus RAE1 RNA export 1 homolog (S. pombe) (Rae1) as transfection-ready DNA NM_001033708.1
Product Type	cDAN Clone
Gene Abbr	Rae1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

RAE1

Background

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

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