Rat Rad23b cDNA Clone(NM_001025275.1)

Name: Rat Rad23b cDNA Clone(NM_001025275.1)
SKU: CDFR003143
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003143

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Product Information

Gene Information

Cat. No.	CDFR003143
Description	NativeORF clone of Rattus norvegicus RAD23 homolog B (S. cerevisiae) (Rad23b) as transfection-ready DNA NM_001025275.1
Product Type	cDAN Clone
Gene Abbr	Rad23b
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

RAD23B

Background

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011]

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