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Rat Rab7a cDNA Clone(NM_023950.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012207

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Gene Information

Cat. No. CDFR012207
Description NativeORF clone of Rattus norvegicus RAB7A, member RAS oncogene family (Rab7a) as transfection-ready DNA NM_023950.3
Product Type cDAN Clone
Gene Abbr Rab7a
Species Rat
Vector pCMV6Entry
Target Gene RAB7A
Background RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
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