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Rat Qdpr cDNA Clone(NM_022390.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011839

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Gene Information

Cat. No. CDFR011839
Description NativeORF clone of Rattus norvegicus quinoid dihydropteridine reductase (Qdpr) as transfection-ready DNA NM_022390.1
Product Type cDAN Clone
Gene Abbr Qdpr
Species Rat
Vector pCMV6Entry
Target Gene QDPR
Background This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. [provided by RefSeq, Jul 2008]
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