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Rat Pyy ORF Clone(NM_001034080.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371372

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Gene Information

Cat. No. CDCR371372
Product Type ORF Clone
Gene Abbr Pyy
Species Rat
Tag C-terminal Myc-DDK
ORF Size 297 bp
Vector pCMV6-Entry
Target Gene PYY
Background This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]
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