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Rat Pts ORF Clone(NM_017220.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378284

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Gene Information

Cat. No. CDCR378284
Product Type ORF Clone
Gene Abbr Pts
Species Rat
Tag C-terminal Myc-DDK
ORF Size 435 bp
Vector pCMV6-Entry
Target Gene PTS
Background The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq, Oct 2008]
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