Transfected Stable Cell Lines
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Cat. No. : CDFR012756
| Cat. No. | CDFR012756 |
| Description | NativeORF clone of Rattus norvegicus protein tyrosine phosphatase, receptor type, N polypeptide 2 (Ptprn2) as transfection-ready DNA NM_031600.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Ptprn2 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | PTPRN2 |
| Background | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] |
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