Rat Ptp4a2 cDNA Clone(NM_053475.1)

Name: Rat Ptp4a2 cDNA Clone(NM_053475.1)
SKU: CDFR013206
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013206

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Product Information

Gene Information

Cat. No.	CDFR013206
Description	NativeORF clone of Rattus norvegicus protein tyrosine phosphatase 4a2 (Ptp4a2) as transfection-ready DNA NM_053475.1
Product Type	cDAN Clone
Gene Abbr	Ptp4a2
Species	Rat
Vector	pCMV6Entry

Target Gene

PTP4A2

Background

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]

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