Transfected Stable Cell Lines
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Cat. No. : CDCR380026
| Cat. No. | CDCR380026 |
| Product Type | ORF Clone |
| Gene Abbr | Ptger4 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 1467 bp |
| Vector | pCMV6-Entry |
| Target Gene | PTGER4 |
| Background | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008] |
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