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Rat Ptger4 ORF Clone(NM_032076.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380026

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Gene Information

Cat. No. CDCR380026
Product Type ORF Clone
Gene Abbr Ptger4
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1467 bp
Vector pCMV6-Entry
Target Gene PTGER4
Background The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
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