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Rat Ptf1a cDNA Clone(NM_053964.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013671

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Gene Information

Cat. No. CDFR013671
Description NativeORF clone of Rattus norvegicus pancreas specific transcription factor, 1a (Ptf1a) as transfection-ready DNA NM_053964.1
Product Type cDAN Clone
Gene Abbr Ptf1a
Species Rat
Vector pCMV6Entry
Target Gene Ptf1a
Background Enables DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in several processes, including neural retina development; regulation of neural retina development; and retinoic acid receptor signaling pathway. Acts upstream of or within several processes, including neuron fate commitment; positive regulation of transcription by RNA polymerase II; and retina morphogenesis in camera-type eye. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; epidermis; eye; foregut-midgut junction; and genitourinary system. Used to study pancreatic carcinoma. Human ortholog(s) of this gene implicated in pancreatic agenesis 2. Orthologous to human PTF1A (pancreas associated transcription factor 1a). [provided by Alliance of Genome Resources, Feb 2025]
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