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Rat Pspc1 cDNA Clone(NM_001025672.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004028

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Gene Information

Cat. No. CDFR004028
Description NativeORF clone of Rattus norvegicus paraspeckle component 1 (Pspc1) as transfection-ready DNA NM_001025672.1
Product Type cDAN Clone
Gene Abbr Pspc1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PSPC1
Background This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by RefSeq, Aug 2011]
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