Rat Psmd8 ORF Clone(NM_001100831.1)

Name: Rat Psmd8 ORF Clone(NM_001100831.1)
SKU: CDCR372393
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR372393

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Product Information

Gene Information

Cat. No.	CDCR372393
Product Type	ORF Clone
Gene Abbr	Psmd8
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	1062 bp
Vector	pCMV6-Entry

Target Gene

PSMD8

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]

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