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Rat Psmb2 cDNA Clone(NM_017284.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011332

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Gene Information

Cat. No. CDFR011332
Description NativeORF clone of Rattus norvegicus proteasome (prosome, macropain) subunit, beta type 2 (Psmb2) as transfection-ready DNA NM_017284.1
Product Type cDAN Clone
Gene Abbr Psmb2
Species Rat
Vector pCMV6Entry
Target Gene PSMB2
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
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