Rat Psmb10 cDNA Clone(NM_001025637.1)

Name: Rat Psmb10 cDNA Clone(NM_001025637.1)
SKU: CDFR003995
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003995

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Product Information

Gene Information

Cat. No.	CDFR003995
Description	NativeORF clone of Rattus norvegicus proteasome (prosome, macropain) subunit, beta type 10 (Psmb10) as transfection-ready DNA NM_001025637.1
Product Type	cDAN Clone
Gene Abbr	Psmb10
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

PSMB10

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]

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