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Rat Prmt1 cDNA Clone(NM_024363.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012308

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Gene Information

Cat. No. CDFR012308
Description NativeORF clone of Rattus norvegicus protein arginine methyltransferase 1 (Prmt1) as transfection-ready DNA NM_024363.1
Product Type cDAN Clone
Gene Abbr Prmt1
Species Rat
Vector pCMV6Entry
Target Gene PRMT1
Background This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
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