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Rat Prkag2 cDNA Clone(NM_184051.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR015115

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Gene Information

Cat. No. CDFR015115
Description NativeORF clone of Rattus norvegicus protein kinase, AMP-activated, gamma 2 non-catalytic subunit (Prkag2) as transfection-ready DNA NM_184051.1
Product Type cDAN Clone
Gene Abbr Prkag2
Species Rat
Vector pCMV6Entry
Target Gene PRKAG2
Background AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
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