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Rat Prc1 cDNA Clone(NM_001107529.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007216

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Gene Information

Cat. No. CDFR007216
Description NativeORF clone of Rattus norvegicus protein regulator of cytokinesis 1 (Prc1) as transfection-ready DNA NM_001107529.1
Product Type cDAN Clone
Gene Abbr Prc1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PRC1
Background This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
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