Rat Ppfibp1 cDNA Clone(NM_001107896.1)

Name: Rat Ppfibp1 cDNA Clone(NM_001107896.1)
SKU: CDFR007542
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007542

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Product Information

Gene Information

Cat. No.	CDFR007542
Description	NativeORF clone of Rattus norvegicus PTPRF interacting protein, binding protein 1 (liprin beta 1) (Ppfibp1) as transfection-ready DNA NM_001107896.1
Product Type	cDAN Clone
Gene Abbr	Ppfibp1
Species	Rat
Vector	pCMV6Entry

Target Gene

PPFIBP1

Background

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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