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Rat Ppfia1 cDNA Clone(NM_001106320.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006064

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Gene Information

Cat. No. CDFR006064
Description NativeORF clone of Rattus norvegicus protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (Ppfia1) as transfection-ready DNA NM_001106320.2
Product Type cDAN Clone
Gene Abbr Ppfia1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PPFIA1
Background The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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