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Rat Pou5f1 cDNA Clone(NM_001009178.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002101

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Gene Information

Cat. No. CDFR002101
Description NativeORF clone of Rattus norvegicus POU class 5 homeobox 1 (Pou5f1) as transfection-ready DNA NM_001009178.2
Product Type cDAN Clone
Gene Abbr Pou5f1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene POU5F1
Background This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
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