Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR005804
| Cat. No. | CDFR005804 |
| Description | NativeORF clone of Rattus norvegicus nucleoside phosphorylase (Np) as transfection-ready DNA NM_001106031.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Pnp |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | PNP |
| Background | This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008] |
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