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Rat Plcd3 cDNA Clone(NM_001105845.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005577

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Gene Information

Cat. No. CDFR005577
Description NativeORF clone of Rattus norvegicus phospholipase C, delta 3 (Plcd3) as transfection-ready DNA NM_001105845.2
Product Type cDAN Clone
Gene Abbr Plcd3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PLCD3
Background This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
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