Rat Plau cDNA Clone(NM_013085.3)

Name: Rat Plau cDNA Clone(NM_013085.3)
SKU: CDFR010887
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR010887

Inquire for Price

Product Information

Gene Information

Cat. No.	CDFR010887
Description	NativeORF clone of Rattus norvegicus plasminogen activator, urokinase (Plau) as transfection-ready DNA NM_013085.3
Product Type	cDAN Clone
Gene Abbr	Plau
Species	Rat
Vector	pCMV6Entry

Target Gene

PLAU

Background

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *