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Rat Pigp cDNA Clone(NM_001099758.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005234

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Gene Information

Cat. No. CDFR005234
Description NativeORF clone of Rattus norvegicus phosphatidylinositol glycan anchor biosynthesis, class P (Pigp) as transfection-ready DNA NM_001099758.1
Product Type cDAN Clone
Gene Abbr Pigp
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PIGP
Background This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
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