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Rat Pias2 cDNA Clone(NM_053337.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013093

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Gene Information

Cat. No. CDFR013093
Description NativeORF clone of Rattus norvegicus protein inhibitor of activated STAT, 2 (Pias2) as transfection-ready DNA NM_053337.1
Product Type cDAN Clone
Gene Abbr Pias2
Species Rat
Vector pCMV6Entry
Target Gene PIAS2
Background This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2017]
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