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Rat Pfkm cDNA Clone(NM_031715.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012851

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Gene Information

Cat. No. CDFR012851
Description NativeORF clone of Rattus norvegicus phosphofructokinase, muscle (Pfkm) as transfection-ready DNA NM_031715.1
Product Type cDAN Clone
Gene Abbr Pfkm
Species Rat
Vector pCMV6Entry
Target Gene PFKM
Background Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
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