Rat Pex7 cDNA Clone(NM_001034147.1)

Name: Rat Pex7 cDNA Clone(NM_001034147.1)
SKU: CDFR004378
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004378

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Product Information

Gene Information

Cat. No.	CDFR004378
Description	NativeORF clone of Rattus norvegicus peroxisomal biogenesis factor 7 (Pex7) as transfection-ready DNA NM_001034147.1
Product Type	cDAN Clone
Gene Abbr	Pex7
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

PEX7

Background

This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008]

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