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Rat Per2 ORF Clone(NM_031678.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379830

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Gene Information

Cat. No. CDCR379830
Product Type ORF Clone
Gene Abbr Per2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3774 bp
Vector pCMV6-Entry
Target Gene PER2
Background This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]
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