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Rat Pdzk1 cDNA Clone(NM_031712.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012848

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Gene Information

Cat. No. CDFR012848
Description NativeORF clone of Rattus norvegicus PDZ domain containing 1 (Pdzk1) as transfection-ready DNA NM_031712.1
Product Type cDAN Clone
Gene Abbr Pdzk1
Species Rat
Vector pCMV6Entry
Target Gene PDZK1
Background This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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