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Rat Pcmt1 cDNA Clone(NM_013073.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010875

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Gene Information

Cat. No. CDFR010875
Description NativeORF clone of Rattus norvegicus protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 (Pcmt1) as transfection-ready DNA NM_013073.3
Product Type cDAN Clone
Gene Abbr Pcmt1
Species Rat
Vector pCMV6Entry
Target Gene PCMT1
Background This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
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