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Rat Pck1 ORF Clone(NM_198780.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR382235

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Product Information

Gene Information

Cat. No. CDCR382235
Product Type ORF Clone
Gene Abbr Pck1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1869 bp
Vector pCMV6-Entry
Target Gene Pck1
Background Enables phosphoenolpyruvate carboxykinase (GTP) activity. Involved in several processes, including gluconeogenesis; glyceraldehyde-3-phosphate biosynthetic process; and positive regulation of memory T cell differentiation. Acts upstream of or within several processes, including cellular response to potassium ion starvation; glycerol biosynthetic process from pyruvate; and positive regulation of transcription by RNA polymerase II. Is active in cytosol. Is expressed in several structures, including alimentary system; brown fat; cerebral cortex; liver; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Feb 2025]
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