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Rat Pbxip1 cDNA Clone(NM_001100976.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005407

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Gene Information

Cat. No. CDFR005407
Description NativeORF clone of Rattus norvegicus pre-B-cell leukemia homeobox interacting protein 1 (Pbxip1) as transfection-ready DNA NM_001100976.1
Product Type cDAN Clone
Gene Abbr Pbxip1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene PBXIP1
Background The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015]
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