Transfected Stable Cell Lines
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Cat. No. : CDFR013372
| Cat. No. | CDFR013372 |
| Description | NativeORF clone of Rattus norvegicus platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit (Pafah1b3) as transfection-ready DNA NM_053654.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Pafah1b3 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | PAFAH1B3 |
| Background | This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009] |
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