Rat Opn4 cDNA Clone(NM_138860.1)

Name: Rat Opn4 cDNA Clone(NM_138860.1)
SKU: CDFR014286
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014286

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Product Information

Gene Information

Cat. No.	CDFR014286
Description	NativeORF clone of Rattus norvegicus opsin 4 (Opn4) as transfection-ready DNA NM_138860.1
Product Type	cDAN Clone
Gene Abbr	Opn4
Species	Rat
Vector	pCMV6Entry

Target Gene

OPN4

Background

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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