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Rat Opa1 cDNA Clone(NM_133585.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014100

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Gene Information

Cat. No. CDFR014100
Description NativeORF clone of Rattus norvegicus optic atrophy 1 homolog (human) (Opa1), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_133585.3
Product Type cDAN Clone
Gene Abbr Opa1
Species Rat
Vector pCMV6Entry
Target Gene OPA1
Background The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]
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