Transfected Stable Cell Lines
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Cat. No. : CDFR003463
| Cat. No. | CDFR003463 |
| Description | NativeORF clone of Rattus norvegicus oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (Ogdh), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001017461.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Ogdh |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | OGDH |
| Background | This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] |
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