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Rat Oas2 cDNA Clone(NM_001009715.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001967

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Gene Information

Cat. No. CDFR001967
Description NativeORF clone of Rattus norvegicus 2-5-oligoadenylate synthetase 2, 69/71kDa (Oas2) as transfection-ready DNA NM_001009715.1
Product Type cDAN Clone
Gene Abbr Oas2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene OAS2
Background This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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