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Rat Nrxn2 cDNA Clone(NM_053846.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013579

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Gene Information

Cat. No. CDFR013579
Description NativeORF clone of Rattus norvegicus neurexin 2 (Nrxn2) as transfection-ready DNA NM_053846.1
Product Type cDAN Clone
Gene Abbr Nrxn2
Species Rat
Target Gene NRXN2
Background This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010]
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